Ultraslow-microfiltration and microdialysis for in vivo sampling: principle, techniques, and applications
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چکیده
Microfiltration often referred as ultrafiltration (UF) is a sampling method next to microdialysis which is underexposed, and it should not be. In this review we tried to be as complete as possible as far for microfiltration. Ultraslow-microdialysis is far from complete as many microdialysis studies are performed but not always in the light of an ultraslow-flow, we report a few. First, we explain the principles of microfiltration and outline the similarities and differences between microdialysis and microfiltration. After this we will go over the topic biocompatibility of the hollow fiber probes placed in vivo briefly. Then we will summarize what has been done in the field of microfiltration the last 5 years. In addition a few articles about ultraslow-microdialysis will be mentioned briefly and the analytical (detection) devices will be highlighted only shortly as this topic deserves a report on its own.
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